LIMIC MediCAL

Passion for Cardiac Invasive imaging

Corelab Analyses

Analysing your  IVUS, OCT and angiogram projects according to your indicated end-points. 

Training

Interpretation and acquisition training IVUS/OCT for several brands.
Training Ultrasound guided punctures.

Clinical reports

We create clinical reports of your IVUS and OCT acquisitions with standard measurements.

In the clinical report we describe the entire pullback: plaques, stents, minimal luminal area, particularities (like dissections, hematoma’s, thrombus, plaque ruptures) etc.

F.e: A and B show resp. concentric and eccentric fibro-fatty plaque, C shows concentric mixed plaque, fibrofatty and superficial calcium and D shows eccentric mixed plaque, fibro-fatty and superficial calcium with a plaque rupture.

About us

Jurgen Ligthart has been working as radiographer in the interventional cardiology department of the Thorax Center at Erasmus MC in Rotterdam, the Netherlands, since 1982. He became interested in invasive imaging (IVUS) in 1989. Starting in 2006, he has been dedicated full-time to invasive imaging (IVUS, OCT, and intracardiac echo), and since 2008, he has been collaborating with Karen Witberg as part of the invasive imaging team. Jurgen is recognized as an expert in invasive imaging and has contributed to 175 publications.

 

Karen Witberg has been working as an ICU nurse in the interventional cardiology department at the Thorax Center of Erasmus MC Rotterdam, NL since 2005. Since 2007, she has been
working part-time in invasive imaging, and since 2008, she has been a full-time member of the invasive imaging team. She has also contributed to 75 publications.

 

The Invasive Imaging Team established a specialized database in 2008 to store and process imaging-guided procedures. They’ve gathered data from 8800 patients and 30000 imaging pullbacks by July 2023. The team not only collected data but also interpreted a substantial portion of the pullbacks, creating valuable clinical reports. They’re involved in diverse research projects commissioned by Erasmus MC and external partners, showcasing their commitment to advancing medical knowledge. In essence, the team’s accomplishments include building a substantial patient database, deriving clinical insights from it, and contributing significantly to both clinical practice and medical research through their research involvement

Jurgen01
Karen

Projects with our participation

Our corelab activity

In vivo detection of high-risk coronary plaques by radiofrequency intravascular ultrasound and cardiovascular outcome: results of the
ATHEROREMO-IVUS study
Jin M. Cheng†, Hector M. Garcia-Garcia†*, Sanneke P.M. de Boer, Isabella Kardys, Jung Ho Heo, K. Martijn Akkerhuis, Rohit M. Oemrawsingh, Ron T. van Domburg, Jurgen Ligthart, Karen T.Witberg, Evelyn Regar, Patrick W. Serruys, Robert-Jan van Geuns, and Eric Boersma
European Heart Journal (2014) 35, 639–647

 

Analyses of IVUS Virtual Histology 

Changes in renal artery dimensions are associated with clinical response to radiofrequency renal denervation: a series of studies using quantitative angiography and intravascular ultrasound.
Thomas Weber, Jorg Kellermair, Karen T. Witberg, Jurgen Ligthart, Robert J. Melder,Thomas Forstner, and Bernd Eber
Journal of Hypertension 2017, 35:2069–2076

Analyses of renal artery angiograms and intravascular ultrasound at baseline and follow up.

Validation of Resting Diastolic Pressure Ratio Calculated by a Novel Algorithm and Its Correlation With Distal Coronary Artery Pressure to Aortic Pressure, Instantaneous Wave–Free Ratio, and Fractional Flow Reserve  The dPR Study
Jurgen Ligthart, RT*, Kaneshka Masdjedi, MD*, Karen Witberg, RN, Frits Mastik, BSc, Laurens van Zandvoort, BSc, Miguel E. Lemmert, MD,PhD, Jeroen Wilschut, MD, Roberto Diletti, MD, PhD, Peter de Jaegere, MD, PhD, Felix Zijlstra, MD, PhD, Isabella Kardys, MD, PhD, Nicolas M Van Mieghem, MD, PhD, Joost Daemen, MD, PhD
Circ Cardiovasc Interv. 2018;11:e006911. DOI: 10.1161/CIRCINTERVENTIONS.118.006911

Analyses of pressure signals, defining and testing the algorithm 

RESEARCH CORRESPONDENCE
Increase in Coronary Lumen Area and Stent Apposition After Treatment of CTO Using a Coronary Self-Expanding Stent
Selina Vlieger, MSc, Cihan Simsek, MD, PhD, Esther M. de Jong–Salentijn, MSc, David Bouchez, MSc, Auke P.J.D. Weevers, MD, 
Rohit M. Oemrawsingh, MD, PhD, Alexander J.J. IJsselmuiden, MD, PhD
JACC: Cardiovascular Interventions VOL 13, No.4 2020, February 24,2020: 534-41

Analyses of OCT, baseline and follow up with stentstrut details

Pharmacodynamic Effects of Pre-Hospital Administered Crushed Prasugrel in Patients With ST-Segment Elevation Myocardial Infarction
Rosanne F. Vogel, MD, et all
JACC: Cardiovascular Interventions VOL. 14 No. 12, 2021



 Analyses of coronary angiograms, TIMI score and TIMI frame count.

Molecular imaging of coronary plaque vulnarability using 18F-fluocholine PET-MRI in patients with coronary artery disease: validation with optical coherence tomography.
Jochem A.J.van der Pol, Briam Rahel, Yvonne J.M.van Cauteren et all

Research Square August 2024

 Qualitative analysis of OCT and labeling OCT landmarks.

Age-specific sex differences in intravascular ultrasound based coronary atherosclerotic plaque characteristics
Jurgen Ligthart, Marie de Bakker, Karen Witberg et all
American Heart Journal Plus:
Cardiology research and Practice Volume 46 October 2024

 Qualitative analysis of IVUS

Talk to us

Have any questions? We are always open to talk about  how we can help you with your training needs, analyses projects and also setting up your live case projects.